Low molecular weight, drug-like molecules with chemical lattices found in agents with the posted channel activity have been assembled.
ActiTarg-I compound pool counts 1460 molecules available as a set and for cherry-picking.
Channel |
Lattice type |
Kv1.5 |
PhQNHPh |
Kv1.5 |
Ph-thiazolidinones |
Kv1.5 |
PhQNHCHPh |
Kv1.5 |
Aminopyridines |
IKr |
RSO2NHPh |
ActiTarg-I is one of TimTec targeted libraries. Other targeted screening collections of interest are:
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