| ST060266 | ST078925 | ST045849 |
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| MW: 289.67
phenyl 5-chloro-2-oxo-3-hydrobenzoxazole-3-carboxylate
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MW: 406.53 4-[(3-cyano-4-(2-thienyl)-2-5,6,7,8-tetrahydroquinolylthio)methyl]benzoic acid ST078925 analog-substitute to validated inhibitor #6, Figure 3. of the paper
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MW: 447.00 3-(2-adamantanylethyl)-2-[(4-chlorophenyl)azamethylene]-4-oxo-1,3-thiazaperhyd roine-6-carboxylic acid ; 2H-1, 3-thiazine-6-carboxylicacid, 2-[(4-chlorophenyl) imino] tetrahydro-4-oxo-3-(2-tricyclo[3.3.1.13, 7] dec-1-ylethyl-) OGT inhibitor, ST045849, TT04,treatment reduces beta-cell development: |
Contact us to order Please list required amounts.
Prices per compound before shipping are:
- 1mg/$99.00
- 2mg/$155.00
- 3mg/$185.00
- 5mg/$210.00
In addition, TimTec assembled small targeted compound collection of over 300 compounds-analogs based on three validated O-GlcNAc Transferase inhibitors (following the results of the discovery at Department of Microbiology and Molecular Genetics, HUMS)
Reference:
Gross, B.J, Kraybill, B.C., Walker, S. Discovery of O-GlcNAc Transferase Inhibitors. Department of Microbiology and Molecular Genetics, Harvard Medical School. JACS Communications, published on Web 09/29/05; J. Am. Chem. Soc. 2005, 127, 14588-14589.
Discovery of O-GlcNAc Transferase Inhibitors Harvard Medical School
Filhoulaud, G., et al. The hexosamine biosynthesis pathway is essential for pancreatic beta cell development. J Biol Chem. 2009 Sep 4;284(36):24583-94.
Zafir A., Readnower R., et.al. Protein O-GlcNAcylation is a Novel Cytoprotective Signal in Cardiac Stem Cells. Stem Cells. 2012 April; 31(4): 765–775.
1mg/$99.00 2mg/$155.00 3mg/$185.00 5mg/$210.00
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