TimTec Compound Libraries for Screening, Chemical Building Blocks
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TimTec eChemStore 1,680,000+ Screening Compounds, Building Blocks Natural Products and Research Organics, Lab Equipment, Software |
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Sample Handling Weighing, Plating, Compound Library Management |
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Novel BH4-BCL-2 Domain Antagonists Induce BCL-2-Mediated Apoptosis in Triple-Negative Breast CancerSimple Summary Our work has led to the identification of three novel BH4 mimetics, SM216, SM396, and SM949, with nanomolar activities both in vitro and in vivo assays. SM396 binds covalently to the BH4 domain of BCL-2 while the compounds SM216 and SM949 are non-covalent BH4 binders. Our results illustrate that these compounds are highly specific to the triple-negative breast cancer cells with no...
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New Florida LocationMay 2019: TimTec have moved to Tampa, Florida.
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Natural Product Library is now composed of 800 pure natural compounds: NPL-800One more plate is added to the pure Natural Products Library making it NPL-800 compounds. Tap natural bioactivity potential with molecules that are primarily sourced from plants with the remaining samples from bacteria, fungus, and animal sources. TimTec NPL, Natural Product Library, is now composed of 800 pure natural compounds as lead identifying material. Natural molecules tend to be multi-active...
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Privileged Structures: Mesoionic, Aminomorpholines, and Dihydropyridines Some molecular motifs are associated with higher biological activity and are given the "privileged" label when found in molecules that are active at two or more different receptors. Revisiting privileged structures is even more momentous now, when investigators are looking for bi-specific therapeutics and when “rediscovery research” is fueling drug repurposing (1,2). TimTec new selection of... -
FBL-3,200 Fragment-Based Library
Fragments.Rainer Mutsch‘s abstract installation, 2006. Molecular fragment as a part of something yet invisible and more functional structural whole defines Fragment-Based Drug Discovery (FBDD) being used more and more on its own and along with HTS campaigns. FBDD is well established by now with the first fragment-based screening drug being approved, Zelboraf (vemurafenib). FBDD is credited...
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New Products
Natural Product Library is now composed of 800 pure natural compounds: NPL-800
One more plate is added to the pure Natural Products Library making it NPL-800 compounds. Tap natural bioactivity potential with molecules that are primarily sourced from plants with the remaining samples...
Read More...Ancient Chinese cures translate into modern Western medicines
China Daily. November 22, 2011. By Cecily Liu
The Chem-TCM is the most comprehensive database of its kind and translates more than 12,000 chemicals from more than 300 Chinese herbs used in traditional...
Purchase your plates, covers, strips from TimTec
ActiCom-480, active compounds with known activities
ActiCom is TimTec collection of 480 compounds with known activities. All compounds are classified in general therapeutic...
Read More...Inhibitors of Anthrax LF and Activators of Neutrophils
Inhibitors of Anthrax LF and Activators of Neutrophils are available now. Inhibitors of Anthrax LF Product Page Activators...
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