Low molecular weight, drug-like molecules with chemical lattices found in agents with the posted channel activity have been assembled.

ActiTarg-I compound pool counts 1460 molecules available as a set and for cherry-picking.

 Channel

Lattice type

Kv1.5 

PhQNHPh

Kv1.5 

Ph-thiazolidinones

Kv1.5 

PhQNHCHPh

Kv1.5 

Aminopyridines

IKr 

RSO2NHPh

Related Products

ActiTarg-I is one of TimTec targeted libraries. Other targeted screening collections of interest are:

ActiTarg-G GPCR Ligands
ActiTarg-K Kinase Modulators
ActiTarg-P Protease Inhibitors
ActiTarg-S Serpins Inhibitors
ActiTarg-N Nuclear Receptor Ligands
ActiTarg-H HDAC Inhibitor
ActiTarg-CNS Central Nervous System Receptors Modulators Library