Compound Selection

Natural Compounds

Featured Natural Products/Compounds

monastrol Monastrol (ST075209) Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
genipin Genipin (ST080860) Genipin is an aglycone derived from an iridoid glycoside called geniposide present in fruit of Gardenia jasmindides Ellis. Genipin is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking.
anabasine Anabasine Hydrochloride (ST069297)
Insecticide Biomarker Inhibitors of breast cancer aromatase VET: anabasin hydrochloride has no teratogenic properties VET: inhibited rat adrenal mitochondrial 11 beta-hydroxylase and microsomal 21-hydroxylase
cytisine Cytisine (ST008373)
Potent ligand for many nAChR subtypes. Known for analgesic, antihypertensive and inotropic activities. partial agonist of high-affinity nicotinic acetylcholine receptors
gossypol Gossypol (ST065835)
Exhibits multiple biological effects including antifertility and anticancer activity.
gramine Gramine (ST023280)
Vasorelaxing agent acting mainly by antagonism at 5-HT (2A) receptors Toxic to cells, may play defensive role in plants
Harman Harman (ST013856)
Possesses antiplasmodial activity associated with a low cytotoxicity Monoamine oxidase (MAO) inhibitor inhibit HIV replication in H9 lymphocyte cells Antibiotic
Lagochiline Lagochiline (ST059290)
Sedative, hemostatic, hypotensitive effects
Levoglucosenone

Levoglucosenone (ST005503)
Initiates tumor and shows clastogenic activity in mice
Lupinine Lupinine (ST018409)
Antialcoholic affect: reduces aethanol anesthesia
Salsolidine Salsolidine (ST023755)
Competitive inhibitor of catechol-O-methyltransferase Stereoselective competitive inhibitor of the enzyme monoamine oxidase
Solasodine Solasodine (ST023803)
Antiinflammatory activity Steroidal alkaloid solasodine is linked to impaired female sexual behavior of rat offspring Antiproliferative activities against human colon (HT29) and liver (HepG2) cancer cells

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211 ST019364
212 ST023277 Buharidine
213 ST023286
214 ST023290 Gentianine
215 ST023304 peganol
216 ST023305 teraline
217 ST023493 Laudanosine, 1-(3,4-DIMETHOXY-BENZYL)-6,7-DIMETHOXY-2-METHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE
218 ST023509 Coumarin
219 ST023512 Uridine; 1-beta-D-Ribofuranosyluracil
220 ST023754 Salsoline
221 ST023798 MONOCROTALINE
222 ST023810 Liothyronine
223 ST024698 Peracetate Naringenin-7-O-beta-D-(6''-O-para-kumaroil)-glucoside.
224 ST024701 Peracetate Quercetin
225 ST024702 Peracetate Rutine
226 ST024709 Glabranine
227 ST024710 Rutine.
228 ST024724 Deoxycholic acid methyl ester
229 ST024730 Daphnoretine Acetate
230 ST024734 Peracetate Pulicarine
231 ST024766 Folic acid or Pteroylglutamic acid
232 ST024778 Gispiduline
233 ST024779 Peracetate Fraxetine
234 ST028625 BOLDINE
235 ST028628 (+)-Usnic acid
236 ST033520 Chenodeoxycholic acid
237 ST036786 8-Hydroxyquinoline beta-D-glucopyranoside
238 ST037059 Hippuric acid
239 ST038026 Epiandrosterone
240 ST041013 5-iodo-2'-deoxyuridine

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MyriaScreen II – diversity screening library from Sigma-Aldrich and TimTec
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Chemistry reagents, HPLC columns, natural compounds
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