Compound Selection

Natural Compounds

Featured Natural Products/Compounds

monastrol Monastrol (ST075209) Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
genipin Genipin (ST080860) Genipin is an aglycone derived from an iridoid glycoside called geniposide present in fruit of Gardenia jasmindides Ellis. Genipin is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking.
anabasine Anabasine Hydrochloride (ST069297)
Insecticide Biomarker Inhibitors of breast cancer aromatase VET: anabasin hydrochloride has no teratogenic properties VET: inhibited rat adrenal mitochondrial 11 beta-hydroxylase and microsomal 21-hydroxylase
cytisine Cytisine (ST008373)
Potent ligand for many nAChR subtypes. Known for analgesic, antihypertensive and inotropic activities. partial agonist of high-affinity nicotinic acetylcholine receptors
gossypol Gossypol (ST065835)
Exhibits multiple biological effects including antifertility and anticancer activity.
gramine Gramine (ST023280)
Vasorelaxing agent acting mainly by antagonism at 5-HT (2A) receptors Toxic to cells, may play defensive role in plants
Harman Harman (ST013856)
Possesses antiplasmodial activity associated with a low cytotoxicity Monoamine oxidase (MAO) inhibitor inhibit HIV replication in H9 lymphocyte cells Antibiotic
Lagochiline Lagochiline (ST059290)
Sedative, hemostatic, hypotensitive effects
Levoglucosenone

Levoglucosenone (ST005503)
Initiates tumor and shows clastogenic activity in mice
Lupinine Lupinine (ST018409)
Antialcoholic affect: reduces aethanol anesthesia
Salsolidine Salsolidine (ST023755)
Competitive inhibitor of catechol-O-methyltransferase Stereoselective competitive inhibitor of the enzyme monoamine oxidase
Solasodine Solasodine (ST023803)
Antiinflammatory activity Steroidal alkaloid solasodine is linked to impaired female sexual behavior of rat offspring Antiproliferative activities against human colon (HT29) and liver (HepG2) cancer cells

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181 ST092583 8-((1E)-4-phenylthio-2-azabut-1-enyl)-2-[8-((1E)-4-phenylthio-2-azabut-1-enyl) -1,6,7-trihydroxy-3-methyl-5-(methylethyl)(2-naphthyl)]-3-methyl-5-(methylethy l)naphthalene-1,6,7-triol
182 ST092584 8-((1E)-4-indan-5-yloxy-2-azabut-1-enyl)-2-[8-((1E)-4-indan-5-yloxy-2-azabut-1 -enyl)-1,6,7-trihydroxy-3-methyl-5-(methylethyl)(2-naphthyl)]-3-methyl-5-(meth ylethyl)naphthalene-1,6,7-triol
183 ST092585 8-((1E)-4-ethylthio-2-azabut-1-enyl)-2-[8-((1E)-4-ethylthio-2-azabut-1-enyl)-1 ,6,7-trihydroxy-3-methyl-5-(methylethyl)(2-naphthyl)]-3-methyl-5-(methylethyl) naphthalene-1,6,7-triol
184 ST092586 8-((1E)-4-dibenzo[b,d]furan-2-yloxy-2-azabut-1-enyl)-2-[8-((1E)-4-dibenzo[b,d] furan-2-yloxy-2-azabut-1-enyl)-1,6,7-trihydroxy-3-methyl-5-(methylethyl)(2-nap hthyl)]-3-methyl-5-(methylethyl)naphthalene-1,6,7-triol
185 ST092587 8-[(1E)-4-(4-cyclohexylphenoxy)-2-azabut-1-enyl]-2-{8-[(1E)-4-(4-cyclohexylphe noxy)-2-azabut-1-enyl]-1,6,7-trihydroxy-3-methyl-5-(methylethyl)(2-naphthyl)}- 3-methyl-5-(methylethyl)naphthalene-1,6,7-triol
186 ST092971 8-[(1E)-2-(5,6-dimethylbenzimidazol-7-yl)-2-azavinyl]-2-{8-[(1E)-2-(5,6-dimeth ylbenzimidazol-7-yl)-2-azavinyl]-1,6,7-trihydroxy-3-methyl-5-(methylethyl)(2-n aphthyl)}-3-methyl-5-(methylethyl)naphthalene-1,6,7-triol
187 ST092972 1-(3-{(1E)-2-[7-(8-{(1E)-2-[3-(2-oxopyrrolidinyl)phenyl]-2-azavinyl}-1,6,7-tri hydroxy-3-methyl-5-(methylethyl)(2-naphthyl))-2,3,8-trihydroxy-6-methyl-4-(met hylethyl)naphthyl]-1-azavinyl}phenyl)pyrrolidin-2-one
188 ST092973 3-(3-{(1E)-2-[7-(8-{(1E)-2-[3-(2-oxo(1,3-oxazolidin-3-yl))phenyl]-2-azavinyl}- 1,6,7-trihydroxy-3-methyl-5-(methylethyl)(2-naphthyl))-2,3,8-trihydroxy-6-meth yl-4-(methylethyl)naphthyl]-1-azavinyl}phenyl)-1,3-oxazolidin-2-one
189 ST001459 (+)-(4,6-O-Benzylidene)methyl-alpha-D-glucopyranoside
190 ST002790 Methyl cholate
191 ST002792 16?,17?-Epoxypregnenolone acetate
192 ST005095 N-(2-Hydroxyethyl)cytisine
193 ST005096
194 ST005173 skimmianine
195 ST005176 Bucharaine
196 ST005180
197 ST008373 Cytisine
198 ST012031
199 ST012797 Peganine
200 ST012861
201 ST012942
202 ST013860 3'-Adenylic acid
203 ST013862 4-Nitrophenyl N-acetyl-alpha-galactosaminide
204 ST013864 Uridine 5'-monophosphate disodium salt; 5'-Uridilyc acid disodium salt
205 ST013866 p-Nitrophenyl-alpha-galacto
206 ST013870 Phenylalanine ethyl ester
207 ST013873 2'-Deoxycytidine 5'-monophosphate
208 ST013878 2',3',5'-Tri-O-benzoyluridine
209 ST013879 2',3',5'-Tri-O-acetyluridine
210 ST018408 Anabasine

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MyriaScreen II – diversity screening library from Sigma-Aldrich and TimTec
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Chemistry reagents, HPLC columns, natural compounds
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