Compound Selection

Formula: C10H12ClN5O4

MW: 301.69

CAS: 146-77-0

MDL:

TNP:

2-chloro-adenosin; Cl AS; Cl-Ado; 6-AMINO-2-CHLOROPURINE RIBOSIDE; 2-CL-ADO; 2-CHLOROADENOSINE; 2-CHLORO-D-ADENOSINE; 2-CADO

LogP: 0.16

LogS: -2.58

Acceptors: 4

Donors: 5

Rotation Bonds: 5

Chiral Centers: 4

N+O: 9

LIPINSKY: 4

IUPAC: 5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolane-3,4-diol

Smiles: n1(c2c(c(N)nc(n2)Cl)nc1)C1C(C(O)C(O1)CO)O

Specification: Miscellaneous Biochemicals; 13C & 2H Sugars; Biochemistry; Nucleosides and their analogs; Nucleosides, Nucleotides & Related Reagents; Bases & Related Reagents; Carbohydrates & Derivatives; Heterocycles; Nucleotides; Adenosine receptor; Adenosine 6-Amino-2-chloropurine riboside Chemical Properties:

mp 162 C refractive index -50 (C=0.1, H2O) storage temp. Store at +4C solubility H2O: 10 mg/mL, clear, colorless CAS DataBase Reference146-77-0(CAS DataBase Reference) NIST Chemistry ReferenceAdenosine, 2-chloro-(146-77-0) Safety Information WGK Germany 3 RTECS AU7357550 6-Amino-2-chloropurine riboside Usage And Synthesis Chemical Properties:

White to Off-White Crystalline Sold UsageA selective A1-adenosine receptor agonist. Induces apoptosis Biological ActivityMetabolically stable analog of adenosine that behaves as an adenosine receptor agonist (K i values are 300, 80 and 1900 nM for A 1 , A 2A and A 3 receptors respectively). Anticonvulsive in vivo . 6-Amino-2-chloropurine riboside

Chemical Compounds - Natural Compounds

Structure Search Shop Online Download Databases Request a CD
Structure Search eChemStore Download Request CD

Site Search

Compound Search

share

FacebookTwitterLinkedin

Contact Us

Toll Free 800-574-7391
Phone: 302-292-8500
Fax: 302-292-8520

Chem-TCM is the digital database of molecules from plants used in the traditional Chinese medicine
MyriaScreen II – diversity screening library from Sigma-Aldrich and TimTec
ApexScreen is a collection of 5,040 compounds that were selected to represent the diversity of TimTec stock
Chemistry reagents, HPLC columns, natural compounds
innovative software packages for chemical database management, chemical web server, structure drawing, diversity analysis, clustering, HTS and combinatorial chemistry, prediction of LogP/solubility/Pk, and Spectra Management