Featured Natural Products/Compounds

monastrol Monastrol (ST075209) Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
genipin Genipin (ST080860) Genipin is an aglycone derived from an iridoid glycoside called geniposide present in fruit of Gardenia jasmindides Ellis. Genipin is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking.
anabasine Anabasine Hydrochloride (ST069297)
Insecticide Biomarker Inhibitors of breast cancer aromatase VET: anabasin hydrochloride has no teratogenic properties VET: inhibited rat adrenal mitochondrial 11 beta-hydroxylase and microsomal 21-hydroxylase
cytisine Cytisine (ST008373)
Potent ligand for many nAChR subtypes. Known for analgesic, antihypertensive and inotropic activities. partial agonist of high-affinity nicotinic acetylcholine receptors
gossypol Gossypol (ST065835)
Exhibits multiple biological effects including antifertility and anticancer activity.
gramine Gramine (ST023280)
Vasorelaxing agent acting mainly by antagonism at 5-HT (2A) receptors Toxic to cells, may play defensive role in plants
Harman Harman (ST013856)
Possesses antiplasmodial activity associated with a low cytotoxicity Monoamine oxidase (MAO) inhibitor inhibit HIV replication in H9 lymphocyte cells Antibiotic
Lagochiline Lagochiline (ST059290)
Sedative, hemostatic, hypotensitive effects
Levoglucosenone


Levoglucosenone (ST005503)
Initiates tumor and shows clastogenic activity in mice

Lupinine Lupinine (ST018409)
Antialcoholic affect: reduces aethanol anesthesia
Salsolidine Salsolidine (ST023755)
Competitive inhibitor of catechol-O-methyltransferase Stereoselective competitive inhibitor of the enzyme monoamine oxidase
Solasodine Solasodine (ST023803)
Antiinflammatory activity Steroidal alkaloid solasodine is linked to impaired female sexual behavior of rat offspring Antiproliferative activities against human colon (HT29) and liver (HepG2) cancer cells

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MyriaScreen II – diversity screening library from Sigma-Aldrich and TimTec
ApexScreen is a collection of 5,040 compounds that were selected to represent the diversity of TimTec stock
Chemistry reagents, HPLC columns, natural compounds
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