This activity-aimed set includes low molecular weight drug-like compounds with fragments found in known non-steroidal anti-inflammatory drugs covering variety of targets. About 20 starting drugs fragments are used to assemble the set of 1950 compounds available in 10mmol or 1mg/1mL concentrations and in dry form.
Fragmental representation is summarized in the table below. Custom sub-sets can be created to narrow or expand the pre-designed selection.
| Lattice type | Lattice Type Occurrence | Drug Example |
| Aryl acetic acids | 353 | Acemetacin, Felbinac |
| Quinolines | 300 | GSK256066, Compound 35 (Kyowa Hakko Kirin), Compound 19 (BMS) |
| Amino aryl carboxylic acid | 141 | Etofenamate, Talniflumate |
| Aryl carboxylic acid derivatives | 705 | Clidanac, Tinoridine |
| Aryl butyric acid derivatives | 24 | Bumadizon, Fenbufen |
| Aryl propionic acid derivatives | 158 | Ibuprofen, Suprofen, Oxaprozin |
| Pyrazoles | 680 | Difenamizole, Epirizole |
| Pyrazolones | 586 | Propyphenazone, Suxibuzone |
| Salicylic acid | 71 | Aspirin, Diflunisal,Parsalmide, Olsalazine |
| 2-hydroxyacetic acid | 3 | Benzydamine |
| 1,3,5-trihydropyrimidine-2,4,6-trione | 26 | Bucolome |
| N-(2-pyridyl)carboxamide | 272 | Difenpiramide |
| 1,3-oxazole-2-ylamine | 4 | Ditazol |
| 2-amino-1-phenylethan-1-ol | 28 | Fepradinol |
| methanesulfonamide, thiazinecarboxamide | 106 | Nimesulide, Lexipafant |
| 9-methylenefluorene | 3 | Paranyline |
| 3,4,5-trihydropyrimidin-2-one | 3 | Proquazone |
