Compound Selection

Formula: C20H17NO6

MW: 367.36

CAS: 485-49-4

MDL:

TNP: TNP00145

(r-(r*,s*))-6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-furo(3,4-e)-1,3-benzodioxol-8(6h)-one; [R-(R*,S*)]-6-(5,6,7,8-TETRAHYDRO-6-METHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLIN-5-YL)FURO[3,4-E]-1,3-BENZODIOXOL-8(6H)-ONE; (+)-BICUCULINE; (+)-BIC

LogP: 1.13

LogS: -4.14

Acceptors: 6

Donors: 0

Rotation Bonds: 1

Chiral Centers: 2

N+O: 7

LIPINSKY: 4

IUPAC: (6R)-6-((5R)-6-methyl(5,6,7,8-tetrahydro-2H-1,3-dioxoleno[4,5-g]isoquinolin-5- yl))-6-hydro-2H-1,3-dioxoleno[4',5'-5,6]benzo[b]furan-7-one

Smiles: c12c(cc3c(c1)OCO3)[C@@H]([C@H]1(c3c(OC1=O)c1c(cc3)OCO1))(N(CC2)C)

Specification: Alkaloids; Intermediates & Fine Chemicals; Pharmaceuticals; GABA/Glycine receptor; GABA (+)-Bicuculline Chemical Properties:

mp 193-197 C storage temp. 0-6C Merck 13,1207 CAS DataBase Reference485-49-4(CAS DataBase Reference) EPA Substance Registry SystemFuro[3,4-e]-1,3- benzodioxol-8(6H)-one, 6-[(5S)-5,6,7,8-tetrahydro- 6-methyl-1,3-dioxolo[4,5- g]isoquinolin-5-yl]-, (6R)-(485-49-4) Safety Information Hazard Codes T,N,Xn Risk Statements 23/24/25-50-36/37/38-20/21/22 Safety Statements 36/37-45-61-36-26 RIDADR UN 1544 6.1/PG 2 WGK Germany 3 RTECS LV0909840 F 10-23 HazardClass 6.1(b) PackingGroup III (R-(R*,S*))-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-furo(3,4-e)-1,3-benzodioxol-8(6H)-one English (+)-Bicuculline Usage And Synthesis Chemical Properties:

Pale Yellow Solid UsageAlkaloid naturally occurring in the d-form. Shows GABA antagonist activity. Biological ActivityClassical GABA A antagonist. (+)-Bicuculline

Chemical Compounds - Natural Compounds

Structure Search Shop Online Download Databases Request a CD
Structure Search eChemStore Download Request CD

Site Search

Compound Search

share

FacebookTwitterLinkedin

Contact Us

Phone: 302-292-8500
Fax: 302-292-8520

MyriaScreen II – diversity screening library from Sigma-Aldrich and TimTec
ApexScreen is a collection of 5,040 compounds that were selected to represent the diversity of TimTec stock
Chemistry reagents, HPLC columns, natural compounds
innovative software packages for chemical database management, chemical web server, structure drawing, diversity analysis, clustering, HTS and combinatorial chemistry, prediction of LogP/solubility/Pk, and Spectra Management