***now 480 compounds***

TimTec Natural Compounds are a new library of 480 natural compounds composed of pure natural products as lead identifying materials.

• Solids or freshly prepared DMSO solutions
• Diversity by nature
• Purity by science
• Value by design

The Natural Compounds Library (NPL) can be sold as an entire collection or by plate.

Download Natural Product Library Structures

From Rediscovering Natural Products article published in Chemical and Engeneering News, why the interest in natural compounds is increasing:

1. Combinatorial chemistry's promise to fill drug development pipelines with de novo synthetic small-molecule drug candidates is unfulfilled
2. The practical difficulties of natural products drug discovery are being overcome by advances in separation technologies and in the speed and sensitivity of structure elucidation
3. A compelling case is being made for the intrinsic utility of natural products as sources of drug leads.
   

Read more at Rediscovering Natural products Article

Featured Screening Results for TimTec NPL

TimTec Natural Product Library was screened to identify compounds that significantly reduce infectivity without cytotoxicity. NPL collection counted 280 compounds at the time of the moderate-throughput screening. MTS assay is adaptable to different virus systems.

Out of 280 compounds, 15 molecules showed antiviral activity and were identified as promising models for immunomodulatory agents.

Shaneyfelt, M. E., et al. Natural products that reduce rotavirus infectivity identified by a cell-based moderate-throughput screening assay.

Virology Journal, 2006, 3:68doi:10.1186/1743-422X-3-68

The electronic version of this article is the complete one and can be found online at:

http://www.virologyj.com/content/3/1/68 and http://www.virologyj.com/content/3/1/68/table/T1

Download available compounds that reduce rotavirus infectivity without cytotoxicity.

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